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Custom Oligonucleotide Synthesis

Affinity Ligands

Oligonucletides can be labeled with biotin or digoxigenin* or directly labeled with alkaline phosphatase. A variety of linker arms are available as spacers to minimize steric hindrance.

Besides their importance as nucleic acid probes, biotinylated oligonucleotides are also useful for the purification of DNA binding proteins or cognate DNA molecules by specific hybridization based affinity chromatography. The biotinylated oligonucleotide can be bound to a streptavidin matrix and used for either column or spin chromatography.

Modifications for Oligo Synthesis
Product Catalog No. 50 nmol scale (XX=05) 200 nmol scale (XX=02) 1 umol scale (XX=01) 2 umol scale (XX=03) 10 umol scale (XX=10) 15 umol scale (XX=15)
Biotin
26-6423 $48.00 $48.00 $62.40 $93.60 $499.20 $624.00
Biotin deoxythymidine dT
26-6424 $325.00 $325.00 $422.50 $633.75 $3,380.00 $4,225.00
Biotin multiple additions
26-6421 $324.50 $324.50 $421.85 $632.77 $3,374.80 $4,218.50
Biotin NHS
26-6712 $75.00 $250.00 $327.00 $146.25 $780.00 $975.00
Biotin TEG (15 atom triethylene glycol spacer)
26-6407 $78.00 $78.00 $101.40 $152.10 $811.20 $1,014.00
Desthiobiotin NHS
26-6713 $250.00 $250.00 $325.00 $487.50 $2,600.00 $3,250.00
Digoxigenin
26-6429 $354.00 $354.00 $460.20 $690.30 $1,884.48 $2,355.60
DNP TEG (2, 4-dinitrophenyl)
26-6512 $324.50 $324.50 $421.85 $632.77 $3,374.80 $4,218.50
NTA (Nitrilotriacetate) Oligo Conjugated
26-6444 $350.00 $350.00 $625.00 $937.00 $4,400.00 $5,280.00
pseudoUridine ribo (psi rU)
27-6531 $350.00 $350.00 $455.00 $682.50 $3,640.00 $4,550.00
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