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Custom Oligonucleotide Synthesis
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Oligo Purification Oligo Reconstitution Primer Design Long Oligos Modifications Sample Oligo Report

Long Oligos up to 250 mer

Gene Link specializes in the synthesis of long oligos with complex base modifications and oligo types. This requires greater than 99.5% coupling efficiency. This can only be attained by using reagents of exacting specifications, optimized protocols and state-of-the-art instruments. Gene Link has perfected and maintains these standards.

  • DNA, RNA, Chimeric, 2'0 Methyl, Phosponate, Phosphorothioate, Antisense, shRNA, Taqman available
  • All modifications available. Click here for a complete list of Modifications.
  • Molecular Beacons, TaqMan Probes, Fluorescent Dye labeled oligos and probes
  • Antisense oligos, phosphorothioate oligos
  • New Customers buy one, get one free.
  • Long Oligos Scale of Synthesis and Typical Yield

      Gel Purified (PAGE - PolyAcrylamide Gel Electrophoresis)
    100-150 mer oligo
    Typical Yield
    151-180 mer oligo
    Typical Yield
    181-199 mer oligo
    Typical Yield
    200-250 mer oligo
    Typical Yield
    Scale A260 Units nmols A260 Units nmols A260 Units nmols A260 Units nmols
    1 umol ~5 ~5 ~4 ~2 ~2 ~1 NR NR
    2 umol ~9 ~9 ~7.2 ~3.6 ~3.6 ~1.8 ~1 ~0.5-1
    *NR = Not Recommended

    Actual Trityl Coupling Efficiency of a 210 mer



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