Oligo Purification

Oligo Reconstitution

Primer Design

Long Oligos

Modifications

Sample Oligo Report

End Modifiers

All modifications can be broadly termed as end modifiers as these modify the 5’ or 3’ end. This section contains a list of modifications that are used to modify the ends for conjugation to other modifications or to solid surfaces including magnetic beads. The end modifiers add a reactive functional group which can be used for conjugation. The common functional groups that can be added are amino, carboxyl and thiol. All of these can be combined with different length of spacers (C3, C12, Spacer 9 and 18) to add physical distance of the functional group from the end of the oligonucleotide sequence.

Modifications for Oligo Synthesis
Product	Catalog No.	50 nmol scale (XX=05)	200 nmol scale (XX=02)	1 mmol scale (XX=01)	2 mmol scale (XX=03)	10 mmol scale (XX=10)	15 mmol scale (XX=15)
5'-Adenylation (rApp)	26-6805	$325.00	$475.00	$1,125.00	$1,865.00	Inquire	Inquire
Amino Linker C-12	26-6420	$90.00	$125.00	$220.00	$364.50	Inquire	Inquire
Amino Linker C-6	26-6418	$55.00	$55.00	$110.00	$220.00	$880.00	$1,100.00
Amino Linker C-7 (3')	26-6406	$142.50	$142.50	$213.75	$342.60	$1,710.00	$2,130.75
Amino modifier serinol	26-6715	$385.00	$385.00	$475.00	$575.00	Inquire	Inquire
Cholesterol TEG (15 atom triethylene glycol spacer)	26-6602	$442.50	$442.50	$663.75	$872.50	Inquire	Inquire
Thiol SS-C3	26-6482	$210.00	$210.00	$290.00	$395.00	$2,127.00	$2,450.00
Thiol SS-C6	26-6419	$210.00	$210.00	$290.00	$395.00	$2,127.00	$2,450.00
Universal Support II	26-6575	$18.75	$18.75	$24.37	$37.00	$195.00	$244.00