Oligo Purification

Oligo Reconstitution

Primer Design

Long Oligos

Modifications

Sample Oligo Report

End Modifiers

All modifications can be broadly termed as end modifiers as these modify the 5’ or 3’ end. This section contains a list of modifications that are used to modify the ends for conjugation to other modifications or to solid surfaces including magnetic beads. The end modifiers add a reactive functional group which can be used for conjugation. The common functional groups that can be added are amino, carboxyl and thiol. All of these can be combined with different length of spacers (C3, C12, Spacer 9 and 18) to add physical distance of the functional group from the end of the oligonucleotide sequence.

Modifications for Oligo Synthesis
Product	Catalog No.	50 nmol scale (XX=05)	200 nmol scale (XX=02)	1 mmol scale (XX=01)	10 mmol scale (XX=10)	15 mmol scale (XX=15)
5’ or 3’ biotinylation	26-64XX-XX	90.00	90.00	190.00	Inquire	Inquire
Biotin-TEG	26-64XX-XX	250.00	250.00	350.00	Inquire	Inquire
5’ or 3’ phosphorylation	26-64XX-XX	55.00	55.00	110.00	Inquire	Inquire
5’ or 3’ acridine	26-64XX-XX	90.00	90.00	190.00	Inquire	Inquire
5’ or 3’ amino linker (C3, C6 or C12)	26-64XX-XX	55.00	55.00	110.00	Inquire	Inquire
Spacers C3 and C12 Spacer 9 and 18	26-64XX-XX	150.00	150.00	200.00	Inquire	Inquire
Spacer dexoyribose	26-64XX-XX	150.00	150.00	200.00	Inquire	Inquire
Digoxigenin	26-64XX-XX	350.00	350.00	450.00	Inquire	Inquire
Alkaline Phosphatase#	26-64XX-XX	550.00	550.00	1200.00	Inquire	Inquire
Dabcyl	26-64XX-XX	290.00	290.00	350.00	Inquire	Inquire
Dabcyl dT	26-64XX-XX	310.00	310.00	390.00	Inquire	Inquire
5’ or 3’ fluorescein	26-64XX-XX	90.00	90.00	190.00	Inquire	Inquire
TET, HEX, 6-FAM	26-64XX-XX	150.00	150.00	200.00	Inquire	Inquire
ROX, TAMRA	26-64XX-XX	250.00	250.00	325.00	Inquire	Inquire
Cy5, Cy5.5, Cy3 and Cy3.5	26-64XX-XX	250.00	250.00	325.00	Inquire	Inquire