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DBCO-sulfo-NHS

picture of DBCO-sulfo-NHS

Modification : DBCO-sulfo-NHS

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6929
Click Chemistry
DBCO-S-NHS
Y
Y
Y
316.37
-
PS26-6929.pdf
-
-
-


Catalog NoScalePrice
26-6929-0550 nmol$219.00
26-6929-02200 nmol$219.00
26-6929-011 umol$365.00
26-6929-032 umol$547.50
26-6929-1010 umol$2,920.00
26-6929-1515 umol$3,650.00

Copper-free Click Chemistry Modifications

Cyclooctyne-based modifications offers the ease of copper-free click reagents. These are simple to use and has excellenet click performance in 17 hours or less at room temperature. Gene Link offers 5'-DBCO-TEG for preparing oligos with 5-DBCO and a 15 tom triethylene glycol spacer arm, DBCO-dT for inserting a DBCO group at any position within the oligonucleotide and DBCO-sulfo-NHS Ester is also offered for post-synthesis conjugation reactions. DBCO-modified oligos may be conjugated with azides in organic solvents, such as DMSO, or aqeous buffers. Depending on the azide used, the reaction will go to completion in 4-17 hours at room temperature.


Addition of DBCO-Sulfo-NHS is post synthesis and requires synthesis of oligo with primary amino group.



- DBCO-sulfo-NHS

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