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picture of DBCO-TEG (5')

Modification : DBCO-TEG (5')

Catalog Reference Number
Modification Code
5 Prime
3 Prime
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC

Click Chemistry

Catalog NoScalePrice
26-6928-0550 nmol$310.00
26-6928-02200 nmol$310.00
26-6928-011 umol$415.00
26-6928-032 umol$622.50
26-6928-1010 umol$3,320.00
26-6928-1515 umol$4,150.00
Discounts are available for DBCO-TEG (5')!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

DBCO-TEG and DBCO-dT direct conjugation modifications have been discontinued due to instability and low overall performance. We suggest to use the alternates that are post synthesis conjugation using DBCO-NHS for amino conjugation or DBCO-Maleimide for thiol conjugation.

Click here for a list of post synthesis DBCO Modifications

Cyclooctyne-based modifications offers the ease of copper-free click reagents. These are simple to use and has excellenet click performance in 17 hours or less at room temperature. Gene Link offers 5'-DBCO-TEG for preparing oligos with 5-DBCO and a 15 tom triethylene glycol spacer arm, DBCO-dT for inserting a DBCO group at any position within the oligonucleotide and DBCO-sulfo-NHS Ester is also offered for post-synthesis conjugation reactions. DBCO-modified oligos may be conjugated with azides in organic solvents, such as DMSO, or aqeous buffers. Depending on the azide used, the reaction will go to completion in 4-17 hours at room temperature.

Glen Report 27.1: Technical Brief - DBCO-dT - An Unusual Case of Iodine Sensitivity

- DBCO-TEG (5')

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