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Spacer C12

Spacer C12

Code : [SpC12]

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picture of Spacer C12

Modification : Spacer C12

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6441
Spacers
[SpC12]
Y
Y
Y
264.3
-
PS26-6441.pdf
-
-
-


Catalog NoScalePrice
26-6441-0550 nmol$162.00
26-6441-02200 nmol$162.00
26-6441-011 umol$216.00
26-6441-032 umol$270.00
26-6441-1010 umol$1,728.00
26-6441-1515 umol$2,160.00
Discounts are available for Spacer C12!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Spacer modifications C3, C6, C9, C12 and triethylene glycol Spacer 9 and 18 are used to insert a spacer arm in an oligonucleotide. These modifications can be added in multiple additions when a longer spacer is required. 3'-Spacer C3 CPG may also act as a blocker of exonuclease and polymerase activity at the 3'-terminus. dSpacer is used to introduce a stable abasic site within an oligonucleotide. See "Photo-Cleavable" modification category for photo-cleavable Spacer.

Spacer C12 is a 12-carbon spacer that is used to incorporate a long spacer arm into an oligonucleotide. Spacer C12 can be incorporated in consecutive additions if a longer spacer is required. Spacer C12 is frequently used for solid-phase immobilization of DNA probes or aptamers for microarray applications (1,2), but can be used for any oligonucleotide-based application requiring a long spacer arm.

References
1. Reese, M.O., van Dam, R.M., Scherer, A., Quake, S.R. Microfabricated Fountain Pens for High-Density DNA Arrays. Genome Res. (2003), 13: 2348-2352.
2. Lao, Y-H., Peck, K., Chen, L-C. Enhancement of Aptamer Microarray Sensitivity through Spacer Optimization and Avidity Effect. Anal. Chem. (2006), 81: 1747-1754. - Spacer C12

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