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dideoxy G 5'

picture of dideoxy G 5'

Modification : ddG-5'

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6338
End Blockers
ddG-5'
Y
N
N
313.2
11.5
PS26-6338.pdf
-
-
-


Catalog NoScalePrice
26-6338-0550 nmol$275.00
26-6338-02200 nmol$275.00
26-6338-011 umol$412.00
26-6338-032 umol$742.00
26-6338-1010 umol$3,296.00
26-6338-1515 umol$4,120.00
Discounts are available for ddG-5'!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Dideoxyguanosine (ddG) is a dideoxyribonucleoside that can only be used to block the 5' end. Use ddC-3' or Spacer C3 to block the 3' end from polymerase extension. ddG is a synthetic analog of deoxyguanosine, in ddG, both the 2- and 3-positions of the ribose have a hydrogen (-H) group substituted for the OH group, whereas in dG, only the 2-position is so substituted. ddG is added to the 5-end of an oligo via 5-to-5 synthesis, using a 2,3-ddG, 5-phosphoramidite. Purification must be by PAGE purification, since such an oligo will not have a trityl group (necessary for RPC purification).

ddC-3' should be used as a 3-end blocking moiety (see ddC technical sheet).

- dideoxy G 5'

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