dideoxy A 5' (2'3' ddA)

ddA-5'

Code : [ddA-5]

Modification : ddA-5'

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC

26-6331
End Blockers
[ddA-5]
Y
N
N
297.21
15.4
PS26-6331.pdf
-
-
-

Catalog No	Scale	Price
26-6331-05	50 nmol	$211.00
26-6331-02	200 nmol	$211.00
26-6331-01	1 umol	$315.00
26-6331-03	2 umol	$473.00
26-6331-10	10 umol	$2,523.00
26-6331-15	15 umol	$3,154.00

Discounts are available for ddA-5'!
Modification* Discount Price Structure
1 site/order	List price
2 sites/order	10% discount
3 sites/order	20% discount
4 sites/order	30% discount
5-9 sites/order	50% discount
10+ sites/order	60% discount
*Exceptions apply

Related Modifications
ddC-5'	ddG-5'	Inverted dC (reverse linkage)
ddT-5'	ddC-3'	Inverted dA (reverse linkage)

Dideoxyadenosine (ddA) is a dideoxyribonucleoside that can only be used to block the 5' end. Use ddC-3' or Spacer C3 to block the 3' end from polymerase extension. ddA is a synthetic analog of deoxyadenosine, in ddA, both the 2' and 3' positions of the ribose have a hydrogen (H) group substituted for the OH group, whereas in dA, only the 2'-position is so substituted. ddA is added to the 5'-end of an oligo via 5' to -5' synthesis, using a 2',3' ddA, 5'-phosphoramidite. Purification must be by PAGE purification, since such an oligo will not have a trityl group (necessary for RPC purification).

ddC-3' should be used as a 3'-end blocking moiety (see ddC technical sheet).

- dideoxy A 5' (2'3' ddA)