Quick Order |All Online Ordering|Product Catalog Ordering|Oligo Modifications List|Product Info & Literature|Oligo Design Tools/Resources

4-Thio dU (s4dU)

Search Modifications
picture of 4-Thio dU (s4dU)

Modification : Thio-4 dU (s4dU)

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6445
Others
[s4dU]
Y
Y
Y
306.23
-
PS26-6445.pdf
-
-
-


Catalog NoScalePrice
26-6445-0550 nmol$354.00
26-6445-02200 nmol$354.00
26-6445-011 umol$460.20
26-6445-032 umol$531.00
26-6445-1010 umol$3,681.60
26-6445-1515 umol$4,602.00
Discounts are available for Thio-4 dU (s4dU)!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

6-Thio-dG, 4-Thio-dT and 4-thio-dU are very useful modifications for photo cross-linking and photoaffinity labelling experiments. Oligos containing 2-thio-dT are useful in examining protein-DNA interaction by acting as photosensitizing probes. The thiocarbonyl group in 2-thio-dT is especially interesting in that it is available to react with compounds associating with the minor groove of DNA. 2-Amino-A forms a very stable base pair with T containing three hydrogen bonds but the stability of the base pair with 2-thio-T is greatly diminished. Due to steric interactions between the 2-thio group of thymidine and the 2-amino group of 2-amino-A, the base pair contains only a single hydrogen bond. Oligos containing 2-amino-dA and 2-thio-dT exhibit high affinity for natural oligonucleotides but show little affinity for other similar oligos even of a complementary sequence. - 4-Thio dU (s4dU)

Oligonucleotide Synthesis |  Flourescent Molecular Probes |  Gene Detection Systems |  Tools & Reagents |  Gene Assays |  RNAi
© 2020 Gene Link |  Terms & Conditions |  Licenses |  Privacy Policy |  March 30, 2020 9:03:59 PM