Modification : Iodo-dTCatalog Reference Number
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
5'-Iodo dT modification is available as an Azide dT [Catalog #: 26-6719] for Click Chemistry. 5'-Iodo dT modification has a setup charge of $250.00 for mild synthesis reagents per order. Azide version does not have additional charges
Iodo-dT (5') can be used to introduce an active azide group to the 5'-end of an oligonucleotide. The oligo is chemically synthesized with Iodo-dT at the 5' end and then post synthesis converted to an active azide. The oligo is provided as an azide or 5'-iodo. The selection should be indicated in the comments of the order.
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2. Rostovtsev, V.V., Green, L.G., Fokin, V.V., Sharpless, K.B. A Stepwise Huisgen Cycloaddition Process: Copper(I)-Catalyzed Regioselective Ligation of Azides and Terminal Alkynes. Angew. Chem. Int. Ed. (2002), 41: 2596-2599.
3. Kumar, R., El-Sagheer, A., Tumpane, J., Lincoln, P., Wilhelmsson, L.M., Brown, T. Template-Directed Oligonucleotide Strand Ligation, Covalent Intramolecular DNA Circularization and Catenation Using Click Chemistry. J. Am. Chem. Soc. (2007), 129: 6859-6864.
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