Quick Order |All Online Ordering|Product Catalog Ordering|Oligo Modifications List|Product Info & Literature|Oligo Design Tools/Resources

IRDye QC-1 NHS

Search Modifications
picture of IRDye QC-1 NHS

Modification : IRDye QC-1N

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6674
Quenchers
[IRDyeQC-1]
Y
Y
Y
1145.67
-
PS26-6674.pdf
750
-
-


Catalog NoScalePrice
26-6674-0550 nmol$267.00
26-6674-02200 nmol$397.00
26-6674-011 umol$991.00
26-6674-032 umol$1,750.00
Related Modifications
IRDye700 IRDye800

IRDye QC-1 quencher is a post synthesis conjugation to a primary amino group thus an additional modification with an amino group is required. A C6 or C12 amino group can be placed at the 5' or for the 3' end a C3 or C7 amino and for internal positions an amino modified base is used, e.g Amino dT C6.

YIELD
NHS based modifications are post synthesis conjugation performed using a primary amino group. The yield is lower as compared to direct automated coupling of modifications that are available as amidites. Approximate yield for various scales are given below.

~2 nmol final yield for 50 nmol scale synthesis.
~5 nmol final yield for 200 nmol scale synthesis.
~16 nmol final yield for 1 umol scale synthesis


IRDye QC-1 is a non-fluorescent (dark) quencher compatible with a wide range of visible and near-infrared fluorophores (~500-800 nm). It has a wide available quenching range with the maxima in the range of 700-800 nm. IRDye QC-1 quenches common fluorophores with >97% efficiency. It is ideal for all IR dyes. - IRDye QC-1 NHS

Oligonucleotide Synthesis |  Flourescent Molecular Probes |  Gene Detection Systems |  Tools & Reagents |  Gene Assays |  RNAi
© 2020 Gene Link |  Terms & Conditions |  Licenses |  Privacy Policy |  October 29, 2020 7:08:19 AM