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Marina Blue

picture of Marina Blue

Modification : Marina Blue

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6687
Fluorescent Dyes
MBlue NHS
Y
Y
Y
284.22
-
PS26-6687.pdf
365
460
-


Catalog NoScalePrice
26-6687-0550 nmol$350.00
26-6687-02200 nmol$350.00
26-6687-011 umol$455.00
26-6687-032 umol$682.00
26-6687-1010 umol$3,640.00
26-6687-1515 umol$4,550.00

Marina Blue is a proprietary dye manufactured by Life Tech/ThermoFisher, it is available as a fluorescent dye that can be conjugated to an oligo, either RNA or DNA. This is a post synthesis conjugation to a primary amino group. The amino group can be placed at the 5' and 3' and for internal positions an amino modified base is used, e.g Amino dT C6


The amine-reactive Marina Blue succinimidyl ester can be used to create blue-fluorescent bioconjugates. Based on the 6,8-difluoro-7-hydroxycoumarin fluorophore, Marina Blue dye exhibits bright blue fluorescence emission near 460 nm and is optimally excited by the intense 365 nm spectra line of the mercury-arc lamp. Because the pKa values of Marina Blue derivatives are 2-3 log units lower than those of the corresponding 7-hydroxycoumarin conjugates, Marina Blue conjugates are strongly fluorescent even at neutral pH. - Marina Blue

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