Custom DNA Conjugation (NHS)

Customer suplied modification has a setup charge of $550.00 per modification type per order. Additional per base/site charges are as listed

On occasion researchers have developed special modified bases or simply have ideas of modified bases that they wish to be incorporated in oligos. Gene Link routinely collaborates extensively with investigators. We assist in the design of oligos with special modification to impart specific characteristics. We also incorporate investigator supplied modified bases and fluorescent dyes in oligos. If it is simply an idea then we collaborate with other labs and companies for the synthesis of these novel modified bases.
See this guide for specifications and requirements. Custom Amidite, NHS & Solid Support Specifications.

This modification is a post synthesis conjugation to a primary amino group thus an additional modification with an amino group is required. A C3, C6 or C12 amino group can be placed at the 5' or for the 3' end a C3 or C7 amino and for internal positions an amino modified base is used, e.g Amino dT C6.