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5-Carboxy-C10

Carboxy-C10

Code : [CO-C10]

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picture of 5-Carboxy-C10

Modification : Carboxy-C10

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6717
Conjugation Chemistry
[CO-C10]
Y
N
N
250.23
-
PS26-6717.pdf
-
-
-


Catalog NoScalePrice
26-6717-0550 nmol$136.00
26-6717-02200 nmol$136.00
26-6717-011 umol$185.00
26-6717-032 umol$210.00
26-6717-1010 umol$778.00
26-6717-1515 umol$1,011.00
Discounts are available for Carboxy-C10!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

5'-Carboxy-Modifier C10 can be used to incorporate an active carboxyl group onto the 5'-end of an oligonucleotide. The carboxyl group is separated from the 5'-end nucleotide base by a 10-carbon spacer arm to minimize steric interaction between the reactive group and the oligo. The presence of the carboxyl group allows the user to 5'-end label the oligo with a variety of different affinity, reporter or protein moieties (as primary amines/thiols or maleimides), depending on the application. Examples include biotin, digoxigenin, fluorescent dyes or quenchers, and enzymes (for example, alkaline phosphatase).

Free Carboxy C10 is supplied as completely deprotected oligo with free carboxyl group ready for conjugation to the selection of functional groups that reacts with carboxyl group.



- 5-Carboxy-C10

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