Convertible dA (O6-Phenyl-deoxy Inosine)

Gene Link supplies Convertible modified oligos protected with oligo bound to CPG solid support or can conjugate the convertible site to user specified ligand.

O6-Phenyl-deoxyinosine (O6-Ph-dI) is classified as a convertible dA nucleotide. After incorporation into an oligo, reaction of the O6-phenyl on the inosine base with a primary amine displaces the oxygen atom, and converts the nucleotide into a N6-substituted dA. Oligos containing O6-Ph-dI modifications are useful precursors in studies requiring a base-modified dA in which the modification is a specific moiety. For example, O6-Ph-dI modified oligos have been reacted with 1,4-diaminobutane(1) in order to subsequently form a DNA molecule with active amines at the N6 position of several A positions in the oligo, for use as part of an affinity purification matrix. Oligos containing O6-Phenyl-dI modifications are also useful precursors in studies requiring cross-linking, at A position(s), between oligos, or between an oligo and an enzyme (2)

See this link for Glen Research Technical Report (pdf) for Convertible bases. Convertible Bases.