Quick Order |All Online Ordering|Product Catalog Ordering|Oligo Modifications List|Product Info & Literature|Oligo Design Tools/Resources

Convertible dA (O6-Phenyl-deoxy Inosine)

Convertible dA (O6-Phenyl-dI)

Code : [O6-Phenyl-dI]

Search Modifications Modified Oligos Quick Price Estimate
picture of Convertible dA (O6-Phenyl-deoxy Inosine)

Modification : Convertible dA (O6-Phenyl-dI)

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC



26-6921
Others
[O6-Phenyl-dI]
Y
Y
Y
830.92
15.4
PS26-6921.pdf
-
-
-


Catalog NoScalePrice
26-6921-0550 nmol$233.00
26-6921-02200 nmol$233.00
26-6921-032 umol$341.00
26-6921-065 umol$1,332.00
26-6921-1010 umol$1,820.00
26-6921-1515 umol$2,729.00
Discounts are available for Convertible dA (O6-Phenyl-dI)!
Modification* Discount Price Structure
1 site/order List price
2 sites/order 10% discount
3 sites/order 20% discount
4 sites/order 30% discount
5-9 sites/order 50% discount
10+ sites/order 60% discount
*Exceptions apply

Gene Link supplies Convertible modified oligos protected with oligo bound to CPG solid support or can conjugate the convertible site to user specified ligand.

O6-Phenyl-deoxyinosine (O6-Ph-dI) is classified as a convertible dA nucleotide. After incorporation into an oligo, reaction of the O6-phenyl on the inosine base with a primary amine displaces the oxygen atom, and converts the nucleotide into a N6-substituted dA. Oligos containing O6-Ph-dI modifications are useful precursors in studies requiring a base-modified dA in which the modification is a specific moiety. For example, O6-Ph-dI modified oligos have been reacted with 1,4-diaminobutane(1) in order to subsequently form a DNA molecule with active amines at the N6 position of several A positions in the oligo, for use as part of an affinity purification matrix. Oligos containing O6-Phenyl-dI modifications are also useful precursors in studies requiring cross-linking, at A position(s), between oligos, or between an oligo and an enzyme (2)


See examples below of Convertible dA (O6-Phenyl-deoxy Inosine) to various amino derivatives.



See this link for Glen Research Technical Report (pdf) for Convertible bases. Convertible Bases.



See this link for Glen Research Technical Report for Convertible bases. Convertible Bases.

References
1. Larson, C.J.; Verdine, G.L. A High-Capacity Column for Affinity Purification of Sequence-Specific DNA Binding Proteins. Nucleic Acids Res. (1992), 30: 3525.
2. Corn, J.E.; Berger, J.M. FASTDXL. Structure (2007), 15: 773-780.
- Convertible dA (O6-Phenyl-deoxy Inosine)

Oligonucleotide Synthesis |  Flourescent Molecular Probes |  Gene Detection Systems |  Tools & Reagents |  Gene Assays |  RNAi
© 2024 Gene Link |  Terms & Conditions |  Licenses |  Privacy Policy |  May 29, 2024 8:51:27 PM