diaminopurine (2-6-diaminopurine)

2-6-diaminopurine

Code : [2-6-AP]

Modification : 2-6-diaminopurine

Catalog Reference Number
Category
Modification Code
5 Prime
3 Prime
Internal
Molecular Weight (mw)
Extinction Coeficient (ec)
Technical Info (pdf)
Absorbance MAX
Emission MAX
Absorbance EC

26-6504
Duplex Stability
[2-6-AP]
Y
Y
Y
328.22
8.5
PS26-6504.pdf
260
-
-

Catalog No	Scale	Price
26-6504-05	50 nmol	$385.00
26-6504-02	200 nmol	$385.00
26-6504-01	1 umol	$410.00
26-6504-03	2 umol	$475.00
26-6504-10	10 umol	$1,685.00
26-6504-15	15 umol	$2,106.00

Discounts are available for 2-6-diaminopurine!
Modification* Discount Price Structure
1 site/order	List price
2 sites/order	10% discount
3 sites/order	20% discount
4 sites/order	30% discount
5-9 sites/order	50% discount
10+ sites/order	60% discount
*Exceptions apply

Diaminopurine (2,6-diaminopurine); 2-6AP is more commonly known as 2-Amino-dA.

2-6 diamino puriene has been used to the design of high affinity primers and probes by substituting an A sites with 2-amino-A, since the 2-amino-A-T base pair is equivalent in strength to the G-T base pair. 2-Amino-A also destabilizes A-G wobble mismatches, thus increasing specificity.

Reference
I.V. Kutyavin, et al., Biochemistry, 1996, 35, 11170-11176. - diaminopurine (2-6-diaminopurine)