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The Gene Link DME PCT are specifically manufactured for Applied Biosystems TaqMan® Drug Metabolism Genotyping Assays. DME Assays detect biologically important polymorphisms that reside in complex portions of the genome. These polymorphisms have been associated with certain diseases such as cancer, and have been shown to significantly impact drug efficiency. Where possible all assays have been mapped to the common public allele nomenclature. All TaqMan® DME genotyping assays have proven performance across 180 unique DNA samples.
Gene Link provides over 5,200 Positive Control Templates (PCT) to genotype over 2,600 high value polymorphisms located in regulatory elements and coding regions for 220 drug metabolism and transporter genes. These PCT are manufactured by Gene Link for all Taqman® SNP Genotyping Assays including Drug Metabolism Enzymes(DME Assays).

  • Select individual assays for your drug metabolism studies
  • Study single nucleotide polymorphisms (SNPs), multiple nucleotide polymorphisms (MNPs), and insertions/deletions (In/Dels) on one platform
  • Work confidently — Applied Biosystems bioinformatics mapping, design, and in silico QC means you will study the right SNP
  • Results You Can Rely On — Gene Link manufactured premium synthetic positive control templates (PCT)
  • Get started immediately with ready-to-use assays optimized for Applied Biosystems Real-Time PCR platforms and Positive Control Templates from Gene Link
  • Easy online ordering.
  • NOTICE TO PURCHASER: LIMITED LICENSE
    A license to perform the patented 5’ Nuclease Process for research is obtained by the purchase of (i) both Licensed Probe and Authorized 5' Nuclease Core Kit, (ii) a Licensed 5’ Nuclease Kit, or (iii) license rights from Applied Biosystems.

    The TaqMan® Drug Metabolism Genotyping Assay contains Licensed Probe. Use of this product is covered by one or more of the following US patents and corresponding patent claims outside the US: 5,538,848, 5,723,591, 5,876,930, 6,030,787, 6,258,569, and 5,804,375 (claims 1-12 only). The purchase of this product includes a limited, non-transferable immunity from suit under the foregoing patent claims for using only this amount of product for the purchaser’s own internal research. Separate purchase of an Authorized 5' Nuclease Core Kit would convey rights under the applicable claims of US Patents Nos. 5,210,015 and 5,487,972, and corresponding patent claims outside the United States, which claim 5’ nuclease methods. No right under any other patent claim and no right to perform commercial services of any kind, including without limitation reporting the results of purchaser's activities for a fee or other commercial consideration, is conveyed expressly, by implication, or by estoppels. This product is for research use only. Diagnostic uses under Roche patents require a separate license from Roche. Further information on purchasing licenses may be obtained from the Director of Licensing, Applied Biosystems, 850 Lincoln Centre Drive, Foster City, California 94404, USA.
     

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