Quick Order |All Online Ordering|Product Catalog Ordering|Oligo Modifications List|Product Info & Literature|Oligo Design Tools/Resources

Literature (Product Manuals, Specifications, MSDS)

 SmartBaseTM custom siRNA & ASO Design Service
Catalog No. ProductPDF Guide
27-6730-00SmartBaseTM custom siRNA & ASO Design Service

SmartBaseTM custom siRNA Design Service. Design for Enhanced siRNA Performance.
Gene Link presents various design options for synthesizing effective siRNAs, probes and oligos based on the application. SmartBaseTM siRNA can be synthesized in a predetermined way to exhibit the features that is desired; for instance to increase duplex stability 2'-fluoro C and U bases and 5-methyl dC and 2-Amino dA can be substituted, for nuclease resistance the phosphodiester linkages can be selectively substituted with phosphorothioate and for cellular delivery we may add cholesterol to the synthetic oligonucleotide sequence or modify with thiol or amine for post synthesis conjugation with Cell Penetrating Peptides (CPP's) that are known to aid transport and facilitate cellular uptake.

Oligonucleotide Synthesis |  Flourescent Molecular Probes |  Gene Detection Systems |  Tools & Reagents |  Gene Assays |  RNAi
© 2023 Gene Link |  Terms & Conditions |  Licenses |  Privacy Policy |  November 28, 2023 4:32:56 AM