Modified Oligonucleotides

Modified Oligonucleotides	Synthesis Scale, $/base
Modified Oligonucleotides	50 nmol	200 nmol	1mmol	10mmol	15mmol
Phosphorothioates (S-oligo)*	$3.50	$4.25	$6.50	$50.00	$65.00
Biotin dT	$220.00	$220.00	$310.00	Inquire	Inquire
5′ or 3′ biotinylation	$90.00	$90.00	$190.00	Inquire	Inquire
5′ or 3′ phosphorylation	$55.00	$55.00	$110.00	Inquire	Inquire
5′ or 3′ acridine	$90.00	$90.00	$190.00	Inquire	Inquire
5′ or 3′ fluorescein	$90.00	$90.00	$190.00	Inquire	Inquire
5′ or 3′ amino linker (C3, C6 or C12)	$55.00	$55.00	$110.00	Inquire	Inquire
Minor bases deoxyinosine (dI), deoxyuridine (dU)	$25.00	$25.00	$55.00	Inquire	Inquire
Minor bases 5 bromodeoxycytosine (5-Br-dC), 5 methyl dC, 5 iodo dC, 5 iodo dU, 5 fluoro dU	$75.00	$75.00	$125.00	Inquire	Inquire
Digoxigenin	$275.00	$275.00	$350.00	Inquire	Inquire
Alkaline Phosphatase#	$550.00	$550.00	$1,200.00	-	-
TET, HEX, 6-FAM	$150.00	$150.00	$200.00	-	-
ROX, TAMRA	$250.00	$250.00	$325.00	-	-
Cy5 and Cy3	$250.00	$250.00	$325.00	-	-
*Minimum charges for 15mer applies

PURITY & USE: The "crude" desalted oligonucleotide supplied is suitable for all amplification and sequencing protocols. Gel purified oligos are recommended for synthetic gene construction, ligation and cloning, mutagenesis experiments and for screening libraries.

Shipping
All custom oligos are regularly shipped in 24 hrs. and guaranteed to be shipped within 48 hrs. of receiving order by Express Standard Overnight for guaranteed afternoon delivery. Upon request, Express Priority Overnight shipment will be made for guaranteed morning delivery.